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  1. With the increasing prevalence and incidence of chronic renal failure leading to advanced kidney disease (ESRD), the use of renal transplant therapy is increasing globally. The aim of this study was to determi...

    Authors: Arghavan Malekshahi, Hamidreza Fallah MortezaNejad, Morteza Rahbar Taromsari, Reza Ghanei Gheshlagh and Kourosh Delpasand

    Citation: Renal Replacement Therapy 2020 6:66

    Content type: Research

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  2. Since 2015, the Committee of International Communication on Academic Research of the Japanese Society for Dialysis Therapy has held its Asian symposium during the society’s Annual Congress to discuss the prese...

    Authors: Toru Hyodo, Masafumi Fukagawa, Nobuhito Hirawa, Yoshitaka Isaka, Hidetomo Nakamoto, Pham Van Bui, Khin Thida Thwin and Chanseila Hy

    Citation: Renal Replacement Therapy 2020 6:65

    Content type: Review

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  3. Etelcalcetide is the first intravenously administered calcimimetic agent used to manage secondary hyperparathyroidism (SHPT) in hemodialysis (HD) patients. We evaluated the safety and efficacy of replacing cin...

    Authors: Yuka Kurokawa, Yusuke Kaida, Takuma Hazama, Yosuke Nakayama, Takaomi Otome, Ryo Shibata, Sakuya Ito, Goh Kodama, Nao Nakamura, Takatoshi Kambe, Tomofumi Moriyama, Akiko Nagata, Aki Minami, Ryotaro Ando, Yoshifumi Wada, Miki Sugiyama…

    Citation: Renal Replacement Therapy 2020 6:64

    Content type: Research

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  5. Gastroparesis is frequently overlooked and difficult to treat. The diagnosis of gastroparesis requires standard upper gastrointestinal endoscopy to exclude gastric outlet obstruction and objective evidence dem...

    Authors: Eriko Eguchi

    Citation: Renal Replacement Therapy 2020 6:62

    Content type: Case Report

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  7. There is a higher frequency of advanced chronic kidney disease (CKD) in frail patients than in the general population. This study evaluated frailty status before initiation of dialysis and clarified the progno...

    Authors: Masaki Yoshida, Yurie Takanashi, Takako Harigai, Noriyuki Sakurai, Keiko Kobatake, Hiroaki Yoshida, Satsuki Kobayashi, Takayuki Matsumoto and Kazue Ueki

    Citation: Renal Replacement Therapy 2020 6:60

    Content type: Research

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  8. Complications of acute kidney injury (AKI) are common in patients with coronavirus disease in 2019 (COVID-19). However, clinical characteristics of COVID-19-associated AKI are poorly described. We present two ...

    Authors: Takuya Fujimaru, Keiki Shimada, Takayuki Hamada, Kimio Watanabe, Yugo Ito, Masahiko Nagahama, Fumika Taki, Shutaro Isokawa, Toru Hifumi, Norio Otani and Masaaki Nakayama

    Citation: Renal Replacement Therapy 2020 6:59

    Content type: Case Report

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  9. The expected remaining lifetime of dialysis patients in Japan was only reported in 2003 and has not been reported thereafter. From 2003 to the present, several new therapeutic agents have been introduced. Thes...

    Authors: Shigeru Nakai, Atsushi Wada, Kenji Wakai, Masanori Abe and Kosaku Nitta

    Citation: Renal Replacement Therapy 2020 6:58

    Content type: Research

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  10. Peritoneal dialysis (PD) is associated with various complications, some of which may result in its discontinuation. Pleuroperitoneal communication (PPC) is commonly recognized by the presence of a diaphragmati...

    Authors: Jun Ino, Haruna Kaneko, Eri Kasama, Mio Kodama, Keitaro Sato, Hitoshi Eizumi and Kosaku Nitta

    Citation: Renal Replacement Therapy 2020 6:57

    Content type: Case Report

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  11. Catheter dysfunction, especially omental wrapping, is a serious complication of peritoneal dialysis (PD). Although catheter implantation at a lower site was reported to prevent omental wrapping, this method co...

    Authors: Kyohei Ogawa, Yukio Maruyama, Nanae Matsuo, Yudo Tanno, Ichiro Ohkido, Keita Hirano, Masato Ikeda and Takashi Yokoo

    Citation: Renal Replacement Therapy 2020 6:56

    Content type: Research

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  12. Renal transplant recipients with chronic kidney disease (CKD) often develop abnormal glucose metabolism. Although recent studies have reported the protective effects of sodium-glucose transport protein 2 (SGLT...

    Authors: Ryoichi Miyazaki, Kyoko Miyagi and Misaki Yoshida

    Citation: Renal Replacement Therapy 2020 6:55

    Content type: Case Report

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  13. Hemodialysis patients have a greater risk of cardiovascular disease, their major cause of death. Obesity is a risk factor for arteriosclerosis, cardiovascular disease, and mortality in the general population. ...

    Authors: Takeshi Iida, Satoshi Morimoto, Hidenobu Okuda, Yoshifumi Amari, Takatomi Yurugi, Fumitaka Nakajima and Atsuhiro Ichihara

    Citation: Renal Replacement Therapy 2020 6:54

    Content type: Research

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  14. Cholesterol embolization syndrome (CES) is a disease associating with the systemic cholesterol crystal embolism and end-organ dysfunction due to the atherosclerotic plaque rupture, which is dominantly triggere...

    Authors: Kota Kakeshita, Tsutomu Koike, Teruhiko Imamura, Yu Arisawa, Sayaka Murai, Ayako Shimizu, Taigo Kiyosawa, Hidenori Yamazaki and Koichiro Kinugawa

    Citation: Renal Replacement Therapy 2020 6:53

    Content type: Case Report

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  15. BK polyomavirus (BKPyV) infection after kidney transplantation is an important cause of graft failure among kidney transplant recipient and may cause malignant tumor, although the association between BKPyV inf...

    Authors: Ryoichi Maenosono, Masayoshi Okumi, Kohei Unagami, Hironori Fukuda, Kazuhiko Yoshida, Yoichi Kakuta, Toshio Takagi, Junpei Iizuka, Tomokazu Shimizu, Haruhito Azuma, Yoji Nagashima, Kazunari Tanabe, Kosaku Nitta and Hideki Ishida

    Citation: Renal Replacement Therapy 2020 6:52

    Content type: Case Report

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    The Correction to this article has been published in Renal Replacement Therapy 2020 6:67

  16. The annual survey questionnaires of the Japanese Society for Dialysis Therapy Renal Data Registry (JRDR) were sent to 4458 dialysis facilities at the end of 2018; 4402 facilities (98.7%) responded to the facil...

    Authors: Kosaku Nitta, Masanori Abe, Ikuto Masakane, Norio Hanafusa, Masatomo Taniguchi, Takeshi Hasegawa, Shigeru Nakai, Atsushi Wada, Takayuki Hamano, Junichi Hoshino, Nobuhiko Joki, Shunsuke Goto, Minako Wakasugi, Keiichi Yamamoto and Hidetomo Nakamoto

    Citation: Renal Replacement Therapy 2020 6:51

    Content type: Review

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  17. Metabolic acidosis is common in hemodialysis (HD) patients. The KDOQI guidelines therapeutic goal is pre-dialysis HCO3− ≥ 22 mmol/L. The aim of the study was to evaluate an individualized HCO3− hemodialysis presc...

    Authors: Rita Valério Alves, Hernâni Gonçalves, Karina Lopes, Flora Sofia and Ana Vila Lobos

    Citation: Renal Replacement Therapy 2020 6:50

    Content type: Research

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  18. Hypozincemia contributes to phosphate-induced vascular calcification in model animals of renal failure, but the association between hypozincemia and aortic stenosis (AS) prevalence in patients with end-stage k...

    Authors: Satoshi Matsui, Tomonaga Ameku, Daisuke Takada and Shinji Ono

    Citation: Renal Replacement Therapy 2020 6:49

    Content type: Research

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  19. This study aimed to evaluate cytokine levels in plasma samples over time from living-donor renal transplant recipients with no evidence of pathological and clinical rejection at least 1 year post-procedure.

    Authors: Ayato Ito, Jun Sugimura, Tomohiko Matsuura, Takaya Abe and Wataru Obara

    Citation: Renal Replacement Therapy 2020 6:48

    Content type: Research

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  20. Pregnancy in dialysis patients is rare but challenging both for nephrologists and obstetricians. Although intensified hemodialysis is effective to achieve favorable clinical outcomes in this clinical setting, ...

    Authors: Hiroyuki Arai, Keita P. Mori, Hideki Yokoi, Ken Mizuta, Jumpei Ogura, Ko Suginami, Tomomi Endo, Yoshihiro Ikeda, Takeshi Matsubara, Tatsuo Tsukamoto and Motoko Yanagita

    Citation: Renal Replacement Therapy 2020 6:47

    Content type: Case Report

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  21. Senior–Løken syndrome (SLS) and Bardet–Biedl syndrome (BBS) are ciliopathies. SLS is characterized by retinitis pigmentosa (RP) and familial nephronophthisis, leading to end-stage kidney disease, while BBS is ...

    Authors: Yuko Fujii, Hideki Matsumura, Akihiko Shirasu, Hyogo Nakakura, Satoshi Yamazaki, Naoya Morisada, Kazumoto Iijima and Akira Ashida

    Citation: Renal Replacement Therapy 2020 6:46

    Content type: Case Report

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  22. It has been difficult to sufficiently achieve body-fluid management using blood volume (BV) monitor during hemodialysis (HD) with constant ultrafiltration (UF) rate. Recently, a relative BV change-guided UF co...

    Authors: Susumu Ookawara, Kiyonori Ito, Takayuki Uchida, Keito Tokuyama, Satoshi Kiryu, Takeshi Suganuma, Kyoko Hojyo, Haruhisa Miyazawa, Yuichiro Ueda, Chiharu Ito, Osamu Iimura, Kunihiko Yoshiya, Yoshiyuki Morishita, Norio Hanafusa and Kaoru Tabei

    Citation: Renal Replacement Therapy 2020 6:45

    Content type: Research

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  23. Systemic scleroderma (SSc) involves multiple organs including the skin, the lung, the kidney, and the esophagus. Nowadays, patient life prognosis has substantially improved due to more appropriate management o...

    Authors: Takashi Ishide, Hiroshi Nishi, Hiroko Ambe, Kenjiro Honda, Motonobu Nakamura, Jiro Sato, Kota Yamamoto, Masaaki Sato and Masaomi Nangaku

    Citation: Renal Replacement Therapy 2020 6:44

    Content type: Case Report

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  24. Pemetrexed (PEM) is administered over a long term to patients with non-squamous cell lung cancer as a maintenance therapy after platinum combination induction chemotherapy. Although decreased renal function ow...

    Authors: Kengo Umehara, Kaori Yama, Nozomi Koike, Shintarou Takayama, Azusa Wakamoto, Tae Hatuyama, Michiya Kobayashi and Hideki Sato

    Citation: Renal Replacement Therapy 2020 6:43

    Content type: Research

    Published on:

  26. The annual survey of the Japanese Society for Dialysis Therapy Renal Data Registry (JRDR) was sent to 4458 dialysis facilities at the end of 2018; among these facilities, 4402 facilities (98.7%) responded to t...

    Authors: Kosaku Nitta, Shunsuke Goto, Ikuto Masakane, Norio Hanafusa, Masatomo Taniguchi, Takeshi Hasegawa, Shigeru Nakai, Atsushi Wada, Takayuki Hamano, Junichi Hoshino, Nobuhiko Joki, Masanori Abe, Keiichi Yamamoto and Hidetomo Nakamoto

    Citation: Renal Replacement Therapy 2020 6:41

    Content type: Position statement

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  27. Multiple factors including older age, comorbidities, inflammation, metabolic acidosis, dialysis-related hypercatabolism and anabolic resistance of skeletal muscle, extraction of circulating amino acids through...

    Authors: Ryota Matsuzawa, Shohei Yamamoto, Yuta Suzuki, Yoshifumi Abe, Manae Harada, Takahiro Shimoda, Keigo Imamura, Sachi Yamabe, Haruka Ito, Shun Yoshikoshi and Atsuhiko Matsunaga

    Citation: Renal Replacement Therapy 2020 6:40

    Content type: Research

    Published on:

  28. Protein-energy wasting (PEW) is a frequently observed complication that leads to increased mortality in hemodialysis patients. However, a multifaceted assessment of PEW by combined objective nutritional parame...

    Authors: Shunsuke Yamada, Toshiaki Nakano, Shoji Tsuneyoshi, Hokuto Arase, Sho Shimamoto, Masatomo Taniguchi, Masanori Tokumoto, Hideki Hirakata, Hiroaki Ooboshi, Kazuhiko Tsuruya and Takanari Kitazono

    Citation: Renal Replacement Therapy 2020 6:39

    Content type: Research

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  29. Traditional vascular risk factors such as hypertension, diabetes mellitus, hyperlipidemia, cigarette smoking, and cardiovascular disease with myocardial infarction and atrial fibrillation have been linked to c...

    Authors: Yuta Noguchi, Marina Ito, Mai Mushika, Takuya Ito and Naoto Kawamura

    Citation: Renal Replacement Therapy 2020 6:38

    Content type: Research

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  30. Dialysis membranes that release nitric oxide (NO) from their surface, mimicking one of the functions of endothelial cells, may suppress platelet reactivity during hemodialysis treatment. The aim of the present...

    Authors: Shunichiro Urabe, Kenichi Kokubo, Hiroshi Tsukao, Kozue Kobayashi, Minoru Hirose and Hirosuke Kobayashi

    Citation: Renal Replacement Therapy 2020 6:37

    Content type: Research

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  31. Social frailty—the lack of a connection to society and infrequent social activities—has been reported to be associated with future declines in physical function in elderly individuals. This study aimed to eval...

    Authors: Koki Abe, Yoshinosuke Shimamura, Takuto Maeda, Yoshikazu Kato, Yasuyoshi Yoshimura, Tomomi Tanaka and Hideki Takizawa

    Citation: Renal Replacement Therapy 2020 6:36

    Content type: Research

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  32. Polysulfone (PS) dialyzers are most frequently used worldwide for chronic renal failure patients and they are produced by several manufacturers. Despite using the same materials, differences in biocompatibilit...

    Authors: Mitsuru Kubo, Ryoichi Nakazawa, Kazuhiro Akiyama, Yoshiho Tsunoda, Kazumasa Kimura, Kenji Koide, Yasuhisa Matsushima, Shinji Hasegawa, Koichi Ikeda and Nakanobu Azuma

    Citation: Renal Replacement Therapy 2020 6:35

    Content type: Research

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  33. Septic shock is a life-threatening condition and one of the most common causes of acute kidney injury (AKI). The acrylonitrile-co-methallyl sulfonate surface-treated (AN69ST) membrane used in severe sepsis was...

    Authors: Naoto Nishizaki, Riko Ueno, Yuki Nagayama, Hanako Abe, Akina Matsuda, Akira Mizutani, Kaoru Obinata, Tadaharu Okazaki and Toshiaki Shimizu

    Citation: Renal Replacement Therapy 2020 6:34

    Content type: Case Report

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  34. To our knowledge, there are no preexisting reports concerning rilpivirine (RPV) removal by hemodialysis and peritoneal dialysis.

    Authors: Nanako Oshiro, Kentaro Kohagura, Shoji Tsuneyoshi, Masao Tateyama, Ryo Zamami, Hitoshi Uehara, Jiro Fujita and Yusuke Ohya

    Citation: Renal Replacement Therapy 2020 6:33

    Content type: Case Report

    Published on:

  35. Brain natriuretic peptide (BNP) levels are used as a marker of heart failure, which is the leading cause of morbidity and mortality in dialysis patients. BNP levels increase as renal function declines. The ran...

    Authors: Etsuko Kumagai, Keiko Hosohata, Kazuhiro Furumachi and Shinji Takai

    Citation: Renal Replacement Therapy 2020 6:32

    Content type: Research

    Published on:

  36. Delayed graft function (DGF) can affect short- and long-term allograft outcomes in kidney transplant recipients. One of the pathophysiological pathways in the occurrence of DGF is ischemia-reperfusion injury (...

    Authors: Mina Borran, Simin Dashti-Khavidaki, Azam Alamdari, Neda Naderi and Farzanehsadat Minoo

    Citation: Renal Replacement Therapy 2020 6:31

    Content type: Research

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  37. Rhabdomyolysis may develop into acute kidney injury (AKI), a life-threatening complication. Obese people are at risk for rhabdomyolysis due to prolonged immobilization. However, there are only a few reports of...

    Authors: Kazuhiro Sakai, Hiroki Omizo, Ryo Togashi, Yuto Hayama, Masaki Ueno, Yoshihiro Tomomitsu, Yoshikazu Nemoto, Shinichiro Asakawa, Michito Nagura, Shigeyuki Arai, Osamu Yamazaki, Yoshifuru Tamura, Shunya Uchida, Shigeru Shibata and Yoshihide Fujigaki

    Citation: Renal Replacement Therapy 2020 6:30

    Content type: Case Report

    Published on:

  38. Pembrolizumab, a highly selective humanized monoclonal IgG4κ isotype antibody against PD-1, is one of the immune checkpoint inhibitors approved for treatment of various cancers. The most frequent immune-relate...

    Authors: Manabu Hayata, Masaya Shimanuki, Takehiro Ko, Ryosuke Date, Ami Hamaguchi, Aki Tominaga, Rei Miura, Teruhiko Mizumoto and Masashi Mukoyama

    Citation: Renal Replacement Therapy 2020 6:29

    Content type: Case Report

    Published on:

  39. Endothelial dysfunction starts at an earlier stage in patients with chronic kidney disease (CKD), and induces macro- and microcirculatory impairments. We evaluated whether uremic toxin-lowering therapy could i...

    Authors: Takayasu Ohtake, Yasuhiro Mochida, Kunihiro Ishioka, Hidekazu Moriya, Sumi Hidaka, Masahiro Hirata, Hirokazu Yamada, Hiromichi Kumagai and Shuzo Kobayashi

    Citation: Renal Replacement Therapy 2020 6:28

    Content type: Research

    Published on:

  40. Arteriosclerosis may progress and lead to peripheral arterial disease (PAD) during the waiting period until kidney transplantation in end-stage kidney disease (ESKD) patients. Additionally, contrast-induced ne...

    Authors: Masataka Banshodani, Seiji Marubayashi, Sadanori Shintaku, Tomoyasu Sato, Misaki Moriishi, Shinichiro Tsuchiya, Hideki Ohdan and Hideki Kawanishi

    Citation: Renal Replacement Therapy 2020 6:27

    Content type: Case Report

    Published on:

  41. Carbamazepine-induced acute kidney injury is mainly caused by acute tubulointerstitial nephritis. Only one case of carbamazepine-induced eosinophilic granulomatosis with polyangiitis (EGPA) with acute kidney i...

    Authors: Tetsuya Abe, Keiko Nishiyama, Takuya Yamazaki, Ryoma Miyasaka, Yukari Honma, Hiroshi Tominaga, Keiko Hashimoto, Takanori Masaki, Fumi Kamata, Mariko Kamata, Togo Aoyama, Takashi Sano, Yasuo Takeuchi and Shokichi Naito

    Citation: Renal Replacement Therapy 2020 6:26

    Content type: Case Report

    Published on:

  43. Pleuroperitoneal communication is a potential complication of peritoneal dialysis (PD). Of the various treatment strategies for pleuroperitoneal communication, successful treatment with pleurodesis using autol...

    Authors: Satoru Tatematsu, Koji Hosoya and Munekazu Ryuzaki

    Citation: Renal Replacement Therapy 2020 6:24

    Content type: Case Report

    Published on:

  44. Peritonitis is a crucial complication that leads to hospitalization or even death in patients who are undergoing peritoneal dialysis (PD). The incidence of PD-related peritonitis associated with nontuberculous...

    Authors: Kohsuke Terada, Tomohiro Yan, Koji Mugishima, Sayuri Kawasaki, Fumiaki Itagaki, Takehisa Yamada and Yukinao Sakai

    Citation: Renal Replacement Therapy 2020 6:23

    Content type: Case Report

    Published on:

  45. Hemodialysis patients tend to be in “unstable psychological conditions” because of complications and physical activity restriction. This study aimed to investigate unusual psychological factors and their influ...

    Authors: Junko Takahashi, Takaya Abe, Mariko Kaneko, Nariyuki Sasaki, Yumiko Takasawa, Tetsuo Kato, Tomohiko Matsuura, Jun Sugimura, Kentaro Fukumoto, Kotaro Otsuka and Wataru Obara

    Citation: Renal Replacement Therapy 2020 6:22

    Content type: Research

    Published on:

  47. The application of presepsin for diagnosing infections in hemodialysis (HD) patients has not been confirmed yet. In addition, whether presepsin can detect atypical mycobacterial infection or not remains unknown.

    Authors: Jun Shiota

    Citation: Renal Replacement Therapy 2020 6:20

    Content type: Case Report

    Published on:

  48. Peritonitis is a common and clinically important complication in patients receiving peritoneal dialysis (PD). Antibiotic administration is essential for PD-related peritonitis, but routes of administration hav...

    Authors: Kohkichi Morimoto, Hiroyuki Terawaki, Naoki Washida, Takahiro Kasai, Yasushi Tsujimoto, Hidemichi Yuasa, Munekazu Ryuzaki, Yasuhiko Ito, Masashi Tomo and Hidetomo Nakamoto

    Citation: Renal Replacement Therapy 2020 6:19

    Content type: Review

    Published on:

  49. Neurological symptoms sometimes occur in hemodialysis patients, with causes including cerebral infarction, cerebral hemorrhaging, meningitis, and encephalitis. Dialysis disequilibrium syndrome (DDS) is widely ...

    Authors: Miki Uwatoko, Koki Tokunaga, Mako Kawano, Masahisa Kamimura, Yutaro Ibi, Masayuki Otsuka, Masato Minami, Haruhito Yoshimine, Fujio Hamada and Akio Ido

    Citation: Renal Replacement Therapy 2020 6:18

    Content type: Case Report

    Published on:

  50. The association of glycated albumin (GA) with mortality is unclear in chronic hemodialysis patients with diabetes. We investigated the usefulness of GA by comparing it with hemoglobin A1c (HbA1c) in this patie...

    Authors: Ko Hanai, Makoto Akamatsu, Aki Fujimori, Harumichi Higashi, Yumiko Horie, Yoshiaki Itaya, Minoru Ito, Tomoko Kanamaru, Hiroshi Kawaguchi, Kan Kikuchi, Hideo Kobayashi, Machiko Komatsu, Takao Kubota, Kenichi Kudo, Satoshi Kurihara, Ikuto Masakane…

    Citation: Renal Replacement Therapy 2020 6:17

    Content type: Research

    Published on:

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Renal Replacement Therapy

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