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Any BPT (N = 127)
|
Any CRRT (N = 107)
|
CRRT for renal indications (N = 82)
|
CRRT for non-renal indications (N = 33)
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IRRT (N = 28)
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PMX-DHP (N = 42)
|
|---|
|
OR
|
95% CI
|
OR
|
95% CI
|
OR
|
95% CI
|
OR
|
95% CI
|
OR
|
95% CI
|
OR
|
95% CI
|
|---|
|
Odds ratio
|
1.161
|
(0.613–2.200)
|
1.259
|
(0.642–2.465)
|
1.579
|
(0.711–3.506)
|
0.787
|
(0.299–2.072)
|
0.806
|
(0.551–1.179)
|
1.491
|
(0.794–2.798)
|
|
SOFA score
|
1.137
|
(1.051–1.230)
|
1.137
|
(1.051–1.230)
|
1.139
|
(1.052–1.232)
|
1.135
|
(1.049–1.229)
|
1.126
|
(1.040–1.219)
|
1.134
|
(1.048–1.227)
|
|
Lactate level
|
1.010
|
(1.003–1.018)
|
1.010
|
(1.003–1.018)
|
1.011
|
(1.003–1.018)
|
1.011
|
(1.003–1.018)
|
1.011
|
(1.003–1.018)
|
1.009
|
(1.002–1.017)
|
|
AKI stage(Day 1–3)
|
|
0
|
1.000
|
–
|
1.000
|
–
|
1.000
|
–
|
1.000
|
–
|
1.000
|
–
|
1.000
|
–
|
|
1
|
0.902
|
(0.404–2.011)
|
0.898
|
(0.402–2.006)
|
0.905
|
(0.406–2.019)
|
0.895
|
(0.401–1.200)
|
0.881
|
(0.394–1.966)
|
0.925
|
(0.414–2.066)
|
|
2
|
1.679
|
(0.783–3.598)
|
1.690
|
(0.789–3.620)
|
1.664
|
(0.777–3.563)
|
1.631
|
(0.759–3.502)
|
1.671
|
(0.778–3.587)
|
1.736
|
(0.808–3.730)
|
|
3
|
2.427
|
(1.260–4.674)
|
2.337
|
(1.211–4.507)
|
1.997
|
(0.956–4.169)
|
2.650
|
(1.517–4.632)
|
2.799
|
(1.562–5.011)
|
2.575
|
(1.469–4.513)
|
|
Primary site of infection
|
|
Lung
|
1.000
|
–
|
1.000
|
–
|
1.000
|
–
|
1.000
|
–
|
1.000
|
–
|
1.000
|
–
|
|
Urinary tract
|
0.181
|
(0.075–0.439)
|
0.184
|
(0.076–0.442)
|
0.187
|
(0.078–0.450)
|
0.186
|
(0.077–0.450)
|
0.173
|
(0.069–0.430)
|
0.175
|
(0.072–0.424)
|
|
Abdomen
|
0.384
|
(0.209–0.705)
|
0.379
|
(0.205–0.698)
|
0.376
|
(0.204–0.694)
|
0.399
|
(0.218–0.731)
|
0.366
|
( 0.199–0.674)
|
0.364
|
(0.197–0.673)
|
|
Others
|
0.674
|
(0.372–1.222)
|
0.668
|
(0.368–1.212)
|
0.662
|
(0.365–1.201)
|
0.682
|
(0.378–1.231)
|
0.693
|
(0.384–1.249)
|
0.660
|
(0.365–1.195)
|
|
Mechanical ventilation within 24 h
|
0.974
|
(0.559–1.699)
|
0.975
|
(0.368–1.212)
|
0.988
|
(0.567–1.722)
|
1.015
|
(0.581–1.771)
|
1.024
|
(0.586–1.789)
|
0.972
|
(0.558–1.693)
|
|
Inotropes or vasopressors
|
1.360
|
(0.746–2.479)
|
1.343
|
(0.737–2.449)
|
1.298
|
(0.709–2.378)
|
1.388
|
(0.760–2.536)
|
1.441
|
(0.786–2.640)
|
1.367
|
(0.749–2.494)
|
- ORs (95% CI) were estimated using multivariate analysis adjusted for significant covariates in the univariable analysis
- Due to collinearity with the APACHE II score, the SOFA score was used for all analyses
- Variables used for calculating the SOFA score, i.e., GCS score, MAP, PaO2:FiO2 ratio, and platelet count, were not included in the multivariable model
- For all multivariable logistic regression models, the p-values for the Hosmer–Lemeshow test were between 0.165 and 0.254
- BPT blood purification therapy, CRRT continuous renal replacement therapy, IRRT intermittent renal replacement therapy, PMX-DHP polymyxin B immobilized fiber column-direct hemoperfusion, OR odds ratio, CI confidence interval, AKI acute kidney injury
