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| | |
Predialysis potassium
| |
|---|
| | |
<4.6 mEq/L
|
≥4.6 mEq/L
| |
|---|
| | |
ARB(−)
|
ARB(+)
|
ARB(−)
|
ARB(+)
| |
|---|
| | |
Group 1
|
Group 2
|
Group 3
|
Group 4
|
p value
|
|---|
| | |
(n = 27)
|
(n = 36)
|
(n = 66)
|
(n = 131)
| |
|---|
|
Age
|
(Years old)
|
70.2 ± 7.19
|
72.7 ± 6.54
|
70.0 ± 6.56
|
66.8 ± 5.85
|
0.060
|
|
Gender (M to F ratio)
| |
17:10
|
27:9
|
37:29
|
68:63
|
0.087
|
|
Vintage of dialysis
|
(Years)
|
2.18 ± 2.07
|
3.67 ± 2.32
|
6.95 ± 3.31
|
6.17 ± 3.48
|
0.002
|
|
Diabetes
| |
8
|
18
|
18
|
45
|
0.131
|
|
CAD
| |
5
|
5
|
8
|
32
|
0.166
|
|
CHF
| |
3
|
3
|
5
|
7
|
0.710
|
|
Stroke
| |
4
|
5
|
4
|
8
|
0.230
|
|
SBP at the beginning of session
|
(mmHg)
|
132.9 ± 11.6
|
153.7 ± 9.62
|
143.0 ± 9.43
|
153.0 ± 7.52
|
<0.001
|
|
DBP at the beginning of session
|
(mmHg)
|
69.6 ± 5.03
|
73.3 ± 6.00
|
73.6 ± 6.04
|
75.3 ± 4.87
|
0.019
|
|
BUN
|
(mg/dL)
|
59.4 ± 5.15
|
55.4 ± 5.23
|
63.7 ± 5.44
|
65.6 ± 4.58
|
<0.001
|
|
Kt/V
| |
0.87 ± 0.09
|
0.83 ± 0.12
|
0.99 ± 0.11
|
0.99 ± 0.09
|
<0.001
|
|
Alb
|
(g/dL)
|
3.55 ± 0.22
|
3.40 ± 0.23
|
3.62 ± 0.20
|
3.71 ± 0.14
|
<0.001
|
|
Hb
|
(g/dL)
|
10.22 ± 0.39
|
9.75 ± 0.46
|
10.02 ± 0.34
|
10.11 ± 0.26
|
0.016
|
|
CRP
|
(mg/dL)
|
1.45 ± 1.03
|
1.96 ± 2.09
|
0.91 ± 0.63
|
0.69 ± 0.54
|
0.004
|
|
K
|
(mEq/L)
|
4.2 ± 0.2
|
4.2 ± 0.2
|
5.2 ± 0.2
|
5.2 ± 0.2
|
–
|
|
Ca
|
(mg/dL)
|
8.3 ± 0.3
|
8.5 ± 0.2
|
8.6 ± 0.3
|
8.7 ± 0.3
|
0.027
|
|
P
|
(mg/dL)
|
5.1 ± 0.6
|
4.6 ± 0.4
|
5.4 ± 0.4
|
5.5 ± 0.4
|
<0.001
|
|
TC
|
(mg/dL)
|
164.5 ± 21.9
|
142.3 ± 15.6
|
152.8 ± 17.7
|
157.9 ± 18.3
|
0.083
|
|
Blood glucose
|
(mg/dL)
|
131.3 ± 21.8
|
139.6 ± 25.3
|
122.9 ± 20.7
|
118.3 ± 17.3
|
0.040
|
|
AF
| |
4
|
2
|
7
|
8
|
0.363
|
|
Changes of ST–T segment in ECG
| |
6
|
16
|
24
|
55
|
0.230
|
|
HCV infection
| |
2
|
4
|
6
|
6
|
0.464
|
|
ACEI
| |
1
|
1
|
7
|
11
|
0.442
|
|
ARB
| |
0
|
36
|
0
|
131
|
–
|
|
CCB
| |
14
|
30
|
33
|
109
|
<0.001
|
|
beta-B
| |
4
|
8
|
18
|
58
|
0.002
|
|
VD
| |
12
|
19
|
34
|
92
|
0.010
|
|
Weekly dose of erythropoietin/DW
|
(U/w/kg)
|
111.5 ± 41.9
|
146.4 ± 41.4
|
118.6 ± 45.9
|
114.6 ± 44.8
|
0.272
|
|
Observational period
| |
2.66 ± 0.81
|
2.19 ± 0.74
|
3.40 ± 0.71
|
3.65 ± 0.66
|
<0.001
|
|
All-cause death
| |
8
|
24
|
19
|
18
|
<0.001
|
|
Cardiovascular death
| |
5
|
14
|
11
|
13
|
<0.001
|
-
CAD coronary artery disease, CHF congestive heart failure, SBP systolic blood pressure, DBP diastolic blood pressure, BUN blood urea nitrogen, Alb albumin, Hb hemoglobin, CRP C-reactive protein, K serum potassium, Ca calcium, P phosphorus, TC total cholesterol, AF atrial fibrillation, HCV hepatitis C virus, ACEI angiotensin converting enzyme inhibitor, ARB angiotensin II receptor blocker, CCB calcium channel blocker, beta-B beta receptor blocker, VD vitamin D3, DW dry weight